ChIP-seq is a method of analyzing the interaction of protein-DNA complexes. This approach is used to profile histone modifications, transcription factors, and other DNA-related proteins. ChIP-Seq analysis uses chromatin immunoprecipitation (ChIP) and next-generation high-throughput sequencing (NGS).
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An exome is a set of all coding sequences in the genome. It is responsible for the production of proteins and constitutes 1.1% of the human genome sequence. Exome sequencing is a viable alternative to whole genome sequencing as it targets only the protein coding regions responsible for most known disease-related variants. Whole exome sequencing is a high quality, affordable and convenient solution for researching complex and rare diseases, cancer research or the human population studies.